Friday, June 26, 2009
A STRONG HEART BECAUSE OF QUERCETIN
A second study in 2008, a randomized, placebo-controlled crossover trial in 12 healthy men showed biochemical evidence of improved endothelial function with as little as 200 mg/day dosage of quercetin.
When you put these studies together, the results point to how quercetin can carry out an important role in protecting cardiovascular health.
I just found another point I think is significant. There is research that shows quercetin is involved in regulating a gene that protects against LDL cholesterol oxidation. Paraoxonase 1 (PON1) protects low-density lipoprotein (LD) cholesterol from the oxidation process. PON1 is a major anti-atherosclerotic protein component of the “good” cholesterol, high density lipoprotein (HDL) cholesterol.
In one study, researchers investigated the role quercetin played in regulating gene PON1 expression in rats. In short, the researchers found the rats receiving quercetin had an increased expression of PON1 by 35%, and serum PON1 increase of 29%. The study’s author concluded, “Our data suggests that quercetin has anti-atherogenic effect by up-regulating PON1 gene expression and its protective capacity against LDL oxidation.
Let me add one other thought. Quercetin is an anti-inflammatory supplement. Inflammation has a direct affect on the total coronary and will kill you if it is not controlled. But, the inflammation does not limit itself to just the coronary system. If you have sore joints, it is because of inflammation. Therefore, quercetin has a very broad impact on the body.
Thursday, June 25, 2009
CANCER SURVIVAL WITH QUERCETIN & RESVERATROL
Quercetin and Resveratrol are major breakthroughs. Research has demonstrated they have a large number of qualities that protect a person from cancer and at the same time will act to help cure a cancer patient These qualities are becoming even more evident as researchers combine quercetin or resveratrol with other natural compounds to achieve even greater success.
Both quercetin and resveratrol have qualities which have caused researchers to question its ability to prevent cancer. Resveratrol fights cancer by causing cancerous cells to destroy themselves. Resveratrol inhibits the activity of a protein called nuclear-factor Kappa B (NF-kB). This protein nourishes cancer cells promoting their growth. Quercetin has the ability to stifle cell proliferation and improve programmed cell death minimizing DNA damage. These qualities have created an interest as a cancer-preventive nutrient. There is also evidence from epidemiologic studies that strongly recommend quercetin and resveratrol correlate a reduced risk of certain cancers. Research studies have shown their ability to prevent or slow tumor development including cancers of the brain, liver, colon, and other tissues.
Research and clinical evidence of quercetin’s or resveratrol’s effective usefulness in preventing cancer as well as use in therapy is quickly building up. There was an early Phase 1 clinical trial of quercetin in patients with a variety of cancer types. Nine patients out of the total eleven patients in the study experienced a decrease in enzyme activity needed for tumor growth. There were also two patients suffering from advanced cancer that had not responded to chemotherapy. Both of the patients responded to the quercetin with important drops in chemical tumor markers during the period of the study.
It was found, in one study, cancer cells received a double assault when they were pretreated with the antioxidant, resveratrol and irradiation causing cell death, apoptosis. This caused an increase in confidence in resveratrol and quercetin in one group of doctors. Unfortunately, there was a group of doctors who expressed the fear that the antioxidant would protect tumor cells. Dr. Okunieff did not agree. He took the position that the study presented very little evidence to support the fear of tumor protection. Evidence supported the fact that when resveratrol reached its target, it injured the nexus of the malignant cells and at the same time protected the normal tissue from harm.
I hope this information will give the reader reason to ask their doctor direct questions if they are facing a problem involving cancer. Today we know the drug companies do not have any drugs that prevent or cure cancer. We know that today there are natural compounds that will give effective help in preventing and caring for cancer. At the top of my list is resveratrol and quercetin. Even more exciting is the fact that researchers are combining quercetin or resveratrol with curcumin and vitamin D3. These combinations are opening the doors to new areas for research to explore.
QUERCETIN MAKES MY HEART HEALTHY
Heart disease is a major killer in America. Research has found that quercetin and resveratrol can have a direct link to solving this horrible problem. Researchers have found that if an individual increases the dietary intake of quercetin-rich foods, he should experience a reduction in the risk of heart disease being the cause of death. In 2000, Spanish researchers found that red wine carrying quercetin and related antioxidants restricted activity of inflammation promoting NF-kappa in human volunteers, furnishing a large part of the explanation of how red wine lowers heart disease mortality.
British researchers demonstrated in 2004 that when a human ingested quercetin supplements there was substantial lessening of platelet aggregation; indicating another of quercetin’s cardiovascular health benefits is related to lowering the risk of clotting. Later, this same group of researchers demonstrated that dietary intake of quercetin from onion soup also helped stop platelet aggregation. In another study of 30 men with heart disease, Greek cardiologists demonstrated that a red grape polyphenol extract rich in quercetin produced an increasing flow-mediated dilation of the major arteries. This was a potent indicator of endothelial health.
I hope you can see how quercetin has demonstrated repeatedly that it functions to improve the health of the heart and related tissue. I agree more research is needed to further refine our understanding of how quercetin and resveratrol can improve an individual’s health. But, I believe it did wonders to solve my heart problems.
Tuesday, June 23, 2009
CANCER TRIALS AND FAILURE
Right after my family member’s surgery and before her release from the hospital, I found myself in a serious discussion with a doctor who told me about a German Biochemist, named Dr. Otto Warburg. He discovered the “cause of cancer back in 1923”. Dr. Warburg wrote a book titled, “The Metabolism of Tumors”, and in the book he demonstrated the primary cause of cancer as the replacement of oxygen in the respiratory chemistry of normal cells by the fermentation of sugar. The doctor’s finding was the fermentation process can only be initiated in the relative absence of oxygen. Today there is no recognition of Dr. Warburg’s work by western medicine, in alternative medicine there is a growing movement pushing such things as keeping the body in an alkaline state rather than in an acidic state.
Progress in cancer treatment has hardly progressed in the last forty years. Every hospital and cancer center in the United States treats cancer as a production line. It is still the same old approach, surgery, chemotherapy or radiation. The drug company’s still do not have any cures, and when someone steps up and presents a procedure or natural based supplement to successfully treat cancer, they block it and destroy it. There is no profit in curing anyone. But, somehow, quercetin and resveratrol have escaped the wrath of the established medical system. Both are demonstrating that these two natural supplements can protect and cure cancer patients. When nutrition is combined with quercetin and resveratrol, the future can look even brighter and healthier for a cancer patient.
Monday, June 22, 2009
QUERCETIN & RESVERATROL BEAT OBESITY
Obesity is rapidly becoming one of Earth’s major global health problems. Quercetin has captured the attention of scientists and they are eagerly exploring quercetin’s potential as a technology to control fat accumulation. Fat has long been considered inert; a biologically uninteresting tissue. Now science knows the old idea that fat is inert is totally wrong. Today, fat is considered, by many in science, to be a beehive of endocrine activity and metabolic activity producing a large number of hormones, inflammatory cytokines and other molecules which influence health, both good and bad.
Recent research is very exciting; it shows that this flavonoid can by itself or in combination with resveratrol and genistein, have the ability to exert multiple effects directly on fat tissue.
Fat accumulation in aging human fat cells is restricted in culture. This also stops the aging of new fat cells and simultaneously starts apoptosis (the programmed destruction of existing fat cells). Quercetin works to block the intake of glucose from the blood. This deprives fat cells from receiving the raw material needed to produce and gather fat molecules. A University of Georgia research group published a striking report in 2008 in which they reported they could stop fat cell production and increase fat cell death by using either resveratrol or quercetin. When they combined resveratrol and quercetin, lipid accumulation was sharply reduced in cultured fat cells by nearly 70%, and increased fat cell apoptosis by an amazing 310%.
Animal studies have shown support to the potential anti-obesity qualities of quercetin. It is no surprise that quercetin alone or in combination with other nutraceuticals is receiving so much attention from researchers trying to find an effective methodology to block obesity and its many harmful effects on human health and vigor.
Quercetin is a wide spread polyphenol found in apples, onions, and red grapes and has been ignored for years, so others in its class have received all of the attention... In the last two years there has been a tremendous increase in information emerging about the versatile molecule. It is now understood that quercetin fundamentally affects disease processes as different as cancer, obesity, heart disease and asthma. The effects of its powerful antioxidant will reduce inflammation throughout the body. The most astonishing effect is that quercetin may have a direct and independent influence in prolonging life itself, the mechanisms of which are becoming less mysterious to science as they are attracted to the deep inside cellular processes.
Sunday, June 21, 2009
Quercetin and Viral Defense
Research on quercetin is being conducted in many research centers around the world. Researchers in Brazil and Korea have found quercetin was successful in reducing airway resistance (difficulty breathing) more than the adrenaline – like drug albuterol and was equivalent in effect as anti-inflammatory cromolyn. It also performed as well as the potent steroid dexamthasone. Michigan State University explored the impact of dietary flavonoids in their role in systemic anti-inflammatory agents. They knew certain foods acted to lower levels of inflammatory risk factor, C – reactive protein (CRP). Because of this, they started looking for food elements to lower CRP and higher flavonoids were found to successfully lower CRP. Quercetin was at the top of the list of specific flavonoid compounds; thus providing cells the greatest defensive protection. High CRP levels are involved with numerous disease conditions such as obesity, heart disease and lupus. Many researchers now believe it is very important to explore quercetin’s potential for preventing death and disability from a host of major killers.
Garlic has almost 200 compounds. Garlic has been used for centuries to treat and prevent infectious diseases and viral complications. Quercetin is one of the 200 compounds in garlic. Modern science has verified quercetin benefits in preventing viral diseases. Laboratory research on quercetin has acted to reduce reproduction and infection of many viruses, including reparatory syncytial virus (a common causative agent of children’s upper respiratory infection).
Last year Italian researchers discovered that an extract rich in quercetin will up regulate an anti-viral immune response in infected cells. Herpes infected cells responded well to this approach. In an animal study quercetin supplementation was effective in aiding mice to resist an influenza infection following exercise – induced stress. A German nutrition expert Professor Stephan C. Bishoff stated “Quercetin is a most promising compound or disease prevention and therapy.”
Saturday, June 20, 2009
FDA Attempts To Probit Pyridoxamine
Why is Pyridoxamine medically important? Have you ever heard of glycation? I had never heard of it until a couple of days ago, and now I understand why it is important. Glycation increases the speed of degenerative diseases. Glycation occurs when glucose pathologically crosslink’s with a protein, making the product of the crosslink nonfunctional. There is nothing that can stop the glycation process completely. But a number of anti-glycation maneuvers can be added to our daily nutrient program to help. Research has developed a method to break glycated protein crosslink’s, reversing this aging mechanism. The FDA has acted to impede this research with regulatory barriers they have created. These crosslink breakers are referred to as glycation-reversing agents.
Medical importance of pyridoxamine, vitamin B6, is clearly shown in research studies that it prevents chronic disease and suppresses disease growth. This form of B6 is specifically effective in retarding the creation of advanced glycation end products. A quick list of age related health problems that B6 (pyridoxamine) reduced or aided are:
Atherosclerosis
Chronic Inflammation
Cataract Formation
Kidney Failure
Diabetic Complications
Alzheimers disease
One of the advantages of pyridoxamine is that it can be taken in high doses and you would not suffer peripheral neuropathy.
Kidney disease and Type 2 diabetes are two huge markets for the drug companies. If they could develop a drug that slowed the rate of kidney failure, they would have massive income. Research has shown that pyridoxamine slows the kidney failure marker, creatinine, by 68%. It would be terrific if this knowledge was made totally available to the medical community so those suffering from these diseases could benefit. But the drug company doing the research is out of money. Even if they found new funds, there is no guarantee that a new drug would become available now or in the future. If a new drug was developed it would be expensive, whereas, pyridoxamine can give those who suffer these medical problems relief and not break them financially. This twisted way the FDA operates just makes the whole thing a hoax. What really upsets me is that pyridoxamine is found in the food we eat. When we eat a meal we ingest pyridoxamine in small quantities. How does the FDA feel they have the power to ban a vitamin the public consumes in almost every meal? They have defined the safest form of vitamin B6 (pyridoxamine) to be a new drug. I have news for you; B6 has been around ever since time began.
Life Extension Magazine, July, 2009 issue, has a detailed article written by William Faloon. FDA Seeks to Ban Pyridoxamine.
Thursday, June 18, 2009
Stress And Cortisol Almost Shattered My Life 3
How many cups of coffee do you need in the morning to stay awake?
How many donuts or other goodies do you eat to stay awake?
How many beers or shots do you need to get control of yourself?
How often do you go out with your wife and enjoy each other?
Why do you have to have a drink to relax? Why can’t you relax?
If you have kids, why is it you never enjoy the time you have with them?
If you are single, are you happy with your life? Why not?
Here is one of the big questions: When you make love to your partner does it make you happy because you are sharing yourself with your partner or is something always more important?
I have had to deal with the above type of questions too many times and not once was it pleasant. I am not a trained therapist and I cannot tell you how to solve these problems. I cannot do that because until recently I did not understand what was happening to me and so I did not gain much insight.
Let me tell you how I set myself up for the Adrenal Fatigue. I graduated from high school in 1955, and went to work for the phone company climbing telephone poles. In 1957, I got a chance to start college at a local junior college. I joined a club and met a group of men that have had a tremendous impact on my life. I spent two years at that junior college. I got involved in campus politics, became president of the club, wrote a book, and worked a full-time job at Todd Shipyard as a rigger apprentice. I also carried twelve units of classes. There was not much time to sleep and proper sleep is important to maintain good health. I was beginning to create my toxic stress problem with Cortisol.
In 1960 I transferred to a local campus of California State College. I carried twelve units of classes, worked for one of the professors at his home, and started a local fraternity with the hope I could make it a colony of a national fraternity. While I was a student, I became very involved in fraternity and campus politics. I increased the stress because I worked very long hours. I never took time out for a good time. Stress was compounded because I never allowed myself to have an outlet for fun and enjoy the brothers around me. By this time it was really hard to relax at night and just go to sleep. I started to put on weight. Finally, I had a very difficult time trying to understand what I was going to do with my life. I felt I had to have the challenge (another term would be a fight without getting physical) before I was happy. I graduated in 1965.
After graduation I went to work for several corporations. I was successful in every job but I did not necessarily make any friends. I worked the same long hours and with the same driven intent that I had as a student. Then I wanted my own company and opened my Environmental Graphic Design Practice. I had no training in art and I knew nothing about environmental graphics. I did not have anyone to talk to. Somehow I put the pieces of the puzzle together just as I had as a student, and I was successful. Each new project was bigger than what I had already completed. I started out working in a bedroom at home, moved to the garage and then into an industrial park, splitting the rent with an architect. I worked seven days a week, twelve to sixteen hours per day. I never took a day off. I celebrated no holidays. I seldom saw my wife and saw less of the kids. I was always worried or scared of some group of problems. I never found a way to enjoy the success. I competed against two of the best designers and took contracts away from them. When it was all over, I realized they had been my principal teachers. I also discovered that I was much more expensive per hour than they were. My project performance organization allowed me to complete a project in a much more complex manner and still beat their price. Why was I such a mess? I did not drink, but I was really heavy; always tired and angry. The people around me used to say my normal attitude was Anger. I did not understand the problems my wife was having. There was no intimacy between my wife and me. It was not her fault. I just did not have a clue. There was no challenge. We would argue, but it was not the same as a competitive fight. There was no trophy to be won. After twelve years of this hell, I was ready for a big fall and it happened in 1982. The economy went to pieces. I went from billing my time at $75.00 an hour to working in a liquor store for minimum wage. I was shattered and went to pieces. I had no self confidence, no strength; I was always tired. I had no idea what was wrong. The doctors I saw could not offer me any help.
I broke every rule and paid with a lot of pain. I HOPE ANYONE READING THIS CAN BE SMARTER THAN I WAS. IT MAKES ABSOLUTELY NO SENSE TO WIN BIG IF YOU CANNOT ENJOY THE PRIZE. YOU HAVE TO FIND THINGS IN LIFE THAT YOU CAN ENJOY AND YOU HAVE TO FIND SOMEONE YOU CAN ENJOY THEM WITH. THERE IS NOTHING IN THIS LIFE THAT IS WORTH MAKING IT THE ONLY THING IN YOUR LIFE. BOOZE AND DRUGS WILL NOT HELP YOU. ALCOHOLICS ALREADY HAVE ADDISON’S DISEASE. DRUGS WILL NOT WORK; YOU WILL REALLY SCREW YOURSELF UP.
I wish I could tell you I found it very simple to solve my Cortisol problem. It was not easy. First of all, I read everything I could find on health and developed a very angry attitude toward doctors. Durk Pearson’s book was the foundation for my education in alternative medicine. In 2001, a book was published, titled Adrenal Fatigue, The 21st Century Stress Syndrome; written by James L. Wilson, N.D., D.C., Ph.D. When I got the book I could not believe what I read. Dr. Wilson knew exactly what I had been going through. He had actually put a program together so I could overcome the Cortisol problem. My first and probably the most difficult thing for me was to find a way to read the book and remember what I had read. The fatigue made my cognitive processes all scrambled. Fortunately, Dr. Wilson developed a line of supplements designed to help a person overcome Adrenal Fatigue. We were not making much money but somehow we found a way to buy the supplements. I got really lucky on two occasions and was able to talk to Dr. Wilson. He answered a lot of questions which really helped. Talking to Dr. Wilson was a tremendous help for me. He knew what I was going through and gave me confidence to believe in myself. The rest is just history. As I listed earlier, I have overcome Addison’s disease and I am working very hard to put my life together. I recognize that not much has changed over the years. It still takes a lot of energy to rise above the problems we encounter in life and there is no simple solution. We must have faith in ourselves and believe in ourselves. I know there will be many tests in the future and only time will tell if I have the inner strength to overcome the barriers.
Tuesday, June 16, 2009
Stress And Cortisol Almost Shattered My Life
I have to admit I am very angry at what happened to me when I found out I had Addison’s disease. It almost killed me and I had to find out what was happening to me. By accident, I discovered my problem was Cortisol Insufficiency. Not one doctor would talk to me about Cortisol. They were all afraid of being prosecuted for treating Cortisol Insufficiency. It was illegal for a doctor to treat any form of Cortisol problem induced by stress.
Have you ever heard of Cortisol? Cortisol is a hormone produced by the Adrenal glands. There is one adrenal gland on the top of each kidney. Cortisol affects a vast majority of the body’s systems; digestion, neurotransmitters in the brain, and the thyroid gland, to name a few. The list is very long. When your balance of Cortisol is messed up, you are set up for all of the degenerative diseases; I mean cancer, heart disease, diabetes, etc. It robs a man of his manhood and you can no longer give your woman the things she needs most. I also became very weak, no stamina, I lost the ability to solve simple problems. This led me to become one very angry person. I could no longer support myself or my family in a good paying or responsible job. As things got worse I could not get along with anyone. Not only were the emotional problems caused by the Cortisol screwing up my brain chemistry and neurotransmitters, I could not find a way to make anyone understand what was happening to me, because I had no understanding of what was going on. When something would happen, I wanted to fight, but I couldn’t because I did not have the strength or ability to control my legs or balance. So I just withdrew into myself. My wife did not leave me, but our relationship was almost nonexistent. All we did was fight. The kids lost their respect for me and I could not understand what was happening. God, I tried everything I could to find an answer to my problems.
In 1983 I got my first real break. I met Durk Pearson and his wife, Sandy Shaw. I was lucky and got to talk to Durk for almost an hour. He got me started on Alternative Medicine. I read their book, Life Extension, A PRACTICAL SCIENTIFIC APPROACH. It was not until 1997 that I heard about hormone testing and the importance of testosterone. I had read several articles that explained if a man does not have a healthy level of testosterone he would experience fatigue. I had given up trying to get any information from doctors and I heard about a new form of testing using samples of saliva to measure a man’s hormones. I had no idea what the hormones did or why they were important to the operation of the human body. I just knew I wanted to find out how to get rid of the fatigue. Just before I ordered the saliva tests I heard about another serious form of testing being used to identify heavy metal poisoning. I did not have the money and knew my wife would get really angry, still I ordered both tests. When I got the test results back, I really had no way to understand their meaning. It was simple to see that I really did not have any testosterone. But the results did not tell me how to correct the deficiencies for any of the hormones. The heavy metals test did not tell me anything. I was really confused and very depressed.
I made appointments with several doctors and showed them the two tests and asked them to explain what the results for each test meant. None of them would tell me anything. They told me the tests were worthless because I did not use blood tests. Now I was really feeling disgusted and like I had been ripped off. The doctors had charged me several hundred dollars for each appointment and they did nothing. Each appointment took about 10 minutes of the doctor’s time.
While I was trying to figure out the tests and how they could help me I heard about a doctor in Washington. His name is Jonathan Wright. Dr. Wright only practices alternative medicine. I contacted his office and got their address. I sent a letter to Dr. Wright and told him about my problems and asked him to help me find a doctor here in Orange County, California. It took almost two months before I received any response. One of his staff sent me the name and address of a doctor that practices alternative medicine. I called and got an appointment. Then I realized the doctor was a woman and I found out that she did not normally see men as patients. After I met Dr. Connealy I showed her the hormone test and heavy metal test. She was very quick in responding to each test. She looked at the heavy metal test and told me I had a real problem with arsenic and strontium. She explained in detail what the test showed and how I could overcome the heavy metal toxins. Then she looked at the hormone test and told me I had a serious problem because I had flatlined the Cortisol test. She explained how important Cortisol was and why it put my life in danger. I asked her what I could do to overcome the problem and I could not believe her answer. She told me she did not know how to solve the problem and she could not help me. I should have been really upset and angry, but I wasn’t. She had told me the truth and that was the most important thing anyone had done for me in a very long time.
I had to find ways to treat myself. I flatlined for four years and should have died. Before long I was reading anything I could find on health and I started calling any one that I thought might have some idea on how I could fight the Cortisol insufficiency. Somehow, I found the answers and was able to put the puzzle together. In 2006 I was tested again. This time I was normal; there were six saliva samples; two were normal and four were high, a total reversal from the three earlier tests. Now the doctors were more than willing to talk to me, they figured I had Cushing’s syndrome, a tumor that would require surgery. After more tests I was shown to be healthy.
Because of their incompetence I almost lost my wife as I could no longer be a man. Manhood demands more than the ability to fight and use my fists. Sex is an extremely strong and natural need every human has. It makes no difference whether it is a man or a woman. There will be no love and close intimate relationship between a man and woman if they do not fulfill the sexual needs they each have. It has been hard for my wife to understand what has happened to me and I do not blame her. I did not know how to explain to her or the kids what was happening to me. Even in 2006 I was only then starting to understand just how complex this Cortisol problem could be.
I finally had a place to start and rebuild my life. My way of handling problems earlier in my life was to go at the problem directly and it served me well. As I can look back now, I realize I seldom failed to achieve my goals. But I paid a heavy price every time. I achieved success starting in college that my mentor complimented me on. He was right. I had a long list of accomplishments that said I was a winner. Unfortunately, I was just setting myself up for a big fall. Winning is great, but it really does not have any great meaning if you are not satisfied and happy to enjoy your friends and family. I never learned that lesson. None of this Toxic Stress has to happen.
Sunday, May 24, 2009
Alzheimer's Disease and Possible Cure
I am seventy-two years old and many people I know are afraid that it is only a matter of time before I come down with this hated disease. So it is with great joy that I am writing this posting for my blog. A group of Researchers from the University of California at Irvine, California, believe they have found a cure for Alzheimer’s. A CURE FOR ALZHEIMER’S and it is so inexpensive. I have to tell you this is only a preliminary study. No one can promise everyone will be cured,
Still, the researchers are conducting the study because they believe they have found the cure for Alzheimers. This study could open the door to totally new research to discover totally new data leading to solving
Another amazing fact is that the cure has been around for decades and can be found in any health food store. Dr. Abe Hoffer, psychiatrist with a very strong bend toward nutrition, used to teach that this nutrient could cure mental illness. The UC Irvine research presented startling results using Alzheimer’s mice. The mice that suffered from Alzheimer’s had their memory restored and were normal again.
The researchers genetically engineered mice to get the equivalent of Alzheimer’s disease. Mice were used because animals can suffer dementia in the same manner as humans develop beta amyloid plaque in their brains – A distinctive Alzheimer’s feature. They divided the mice into two groups. One group received nothing to combat the Alzheimer’s and the second group received the experimental nutrient for the four months of the research project. A vitamin was added to the second group’s water when they were four months old. Testing began to check the effect of the vitamin on the test group of mice’s short-term memory and long-term memory. Testing showed they found lower levels of phosphorylated tau in the brains of the Alzheimer’s mice that received the nutrient, as well as an increase in proteins that strengthen the brain’s microtubules. Untreated Alzheimer’s mice demonstrated memory loss and those that received the nutrient, performed as well as normal mice.
What nutrient did they use in the research? Vitamin B-3, otherwise known as niacinamide. This is the no flush form of niacin. Almost every health food store has this vitamin in stock and it is not expensive. I purchased a month’s supply for less than $20.00.
Results from this research demonstrated that oral niacinamide is an easily tolerated form of the vitamin B-3, and it is amazing in its ability to treat Alzheimer’s. The research by the team at University of California, Irvine, exhibited in a very clear fashion that oral niacinamide treatment will prevent cognitive deficits in mice with Alzheimer’s. It also improved the short-term memory in mice not suffering from Alzheimer’s. The key achievement of this research was that the infected mice recovered and could function as well in memory testing as healthy mice; suggesting that the vitamin, niacinamide, protected their brains from memory loss and restored memory that had been lost.
The UCI researchers are recruiting patients for a human study. The people taking part in this study will take 1500 mg a niacinamide twice daily. I believe this is a terrific opportunity to take a step forward in protecting ourselves from Alzheimers and do it without making any expensive investment.
I must repeat the warning that you do not want to use niacin. It would give you a very uncomfortable prickly flush. Niacinamide is the no flush form of B-3 and it does not have any irritating effects on the liver, even in high doses.
Several members of the research team have made comments that we should pay attention too. In the Journal of Neuroscience. Dr. Kim Green, commented that, “Cognitively, they were cured”. He goes on to say, “It actually improved behavior in no-demented animals.” Dr. Frank LaFerla, also stated that, “This suggests that not only is it good for Alzheimer’s disease, but if normal people take it, some aspects of their memory might improve.”
Journal of Neuroscience, 2008 November 5; 28(45):11500-10.
Sunday, April 19, 2009
Quercetin Combined with Green Tea and Curcumin
A green tea component, epicatechin, has been combined with quercetin flavonoids to improve endothelial function; this is an important marker of cardiovascular health, in a new human trial.
The cells lining blood vessels are called endothelial. Normally endothelial cells lose their flexibility as we age. It was the object of one research study to learn if green tea component could improve the endothelial function in 12 healthy men. Each member of this group was given 200 mg quercetin, epicatechin, epigallocatechin gallate or a placebo. Nitric oxide was used to determine if the flavonoids were having a beneficial effect on the blood vessel endothelial cells. Nitric oxide was used because it causes the cells to become more flexible and will only work if the rigidity of the cells has been reduced, giving them the ability to expand. Without getting into the technical details of the study, the conclusion was that quercetin and epicatechin, can boost nitric oxide status and reduce endothelin-1 concentrations, improving endothelial function.
Quercetin and Curcumin Found Important for Colon Health
Research is indicating that when quercetin and curcumin, a turmeric-derived component, could possibly reduce precancerous polyps in people who have an inherited tendency to develop colon cancer.
The current study worked to evaluate the effect of the combination of curcumin and quercetin to retard adenomas in patients with FAP. The study had five FAP patients with prior colectomy; each received 480 mg of curcumin and 20 mg of quercetin. The study found the number of polyps were reduced from the start of the project by a mean of 60.4 percent and the size of the polyps were reduced by 50.9 percent. There were minimal negative side effects and no laboratory abnormalities were noted.
In conclusion, it was found that curcumin and quercetin acted to reduce the number and size of ileal and rectal adenomas in patients with FAP without any appreciable toxicity. The researchers are trying to develop and operate randomized controlled trials to validate their findings.
Saturday, April 18, 2009
My Goals for this Blog
Today, when I see people sitting in a doctor’s waiting room I get very up set. I doubt if any of those individuals have any real understanding of why they are sick. The majority just accept what ever the doctor tells them to do; buy a prescription, accept the prescribed surgery or what ever medical methodology that is prescribed. Most doctors will not take any time to explain in detail what the problem is, or what the causative factors are. Very few will explain how to control the causative factors; assuming that all that is solved when the prescription is followed.
I went through this type of routine when I had my heart attack. I lay in that parking lot for 2 hours before I had regained the strength to crawl over to my car. I pulled myself into the driver’s seat, by this time I was soaking wet from sweating and hurt like hell. I had to gasp to breath. I drove to a medical center down the street and went into the Emergency room and asked for help. A nurse checked me over and told me there was nothing wrong. I went out to my car and sat there until the pain in my chest and my back stopped and I could breathe without effort. Several months later my regular doctor ordered an electrocardiogram for me. She told me I had a heart attack and I told her what happened. She called a Cardiologist and made an appointment for me. In short, I went through a series of very dangerous and painful tests, which resulted in my diagnosis. The Cardiologist gave me a fist full of prescriptions and restrictions on my life style. He would not answer any of my questions. I went back to my regular doctor and explained what had happen. My doctor got very angry and called the Cardiologist’s office. From that point on my education started on heart disease. She put me on a number of supplements and herbs. I did not understand how the supplements like Coenzyme Q10, L-Carnitine, D-Ribose, or Magnesium did anything to help my heart, but I faithfully did as the doctor directed, and guess what, my pain disappeared, I did not get dizzy, I had more stamina and strength. I was not totally healed, but I was a hell of a lot better. I knew I had to know what exactly was wrong with my heart and why I had the problem. So I had a lot of questions. My doctor was a practitioner of Alternative medicine. She answered most of my questions and agreed that I needed to learn more. I asked a lot of questions and I will admit it was not easy. But I was fortunate and started getting more and more answers. One day I called a company that had a top quality D-Ribose supplement and I was asking a lot of pointed questions, because I was not a believer in what this supplement was supposed to do. Finally, the lady I was talking to told me about a book written by Stephen T. Sinatra, a practicing cardiologist in Connecticut. The Sinatra Solution, is a fantastic book. It is written for laymen, not doctors; it explained what was wrong with my heart, why I had the problems I had; very clearly explained why the supplements worked to solve my problems. Dr. Sinatra spends a lot of time explaining how each supplement works, what the good points are and bad points. The toughest chapter is where he actually explains the different conditions that can affect the heart. It took me a lot more time to understand what he was trying to get across to the reader. When I finished it I knew how to put a plan together to save my life. I say this because the only person that can be responsible for my life and good health is myself. This is one example of what I mean when I say we have to become informed and responsible before we can improve our health. Doctors can only assist us, but we have to know what they are attempting and why they are going in the direction they have chosen.
I would recommend that you check out two magazines. Life Extension magazine, at www.lifeextension.com; they will send you a copy of the magazine for free. It is a terrific publication. I subscribe to the magazine and I am also a member of the Life Extension Foundation. There are a lot of benefits that they have to offer.
Total Health Magazine is another terrific publication. Go to www.totalhealthmagazine.com
I would also like to recommend a book written by Suzanne Somers, BREAKTHROUGH, EIGHT STEPS TO WELLNESS.
I started reading this book in August. It completely stopped me. I had never given Suzanne Somers any real attention. Man was I wrong. She is an accomplished author and really knows the problems of medicine. In the book she interviews some very accomplished doctors and does not hide the shocking details she learns from the doctors. The first doctor she interviewed was one of my heroes, Dr. Jonathan Wright. This is a book that every one has to read before they can really put their health plans together.
I hope you found some of my thoughts valuable and useful. This is a new adventure for me and I am very excited about how I may be able to help people.
Thursday, April 16, 2009
QUERCETIN & CANCER SURVIVAL
No, I have never had cancer, but members of my family have gone through the hell of cancer. I saw nothing to impress me in the way western medicine cared for the family member. I did not see any thought of innovative care or interest in finding a way to fight the cancer. What I saw was a group of robots that treated every cancer patient the same way; patients and their families were no different. There was absolute acceptance of their doom. The fatalistic depression gave these so-called doctors total freedom to do anything they chose to do. All of their brilliant treatments centered on the same series of treatment; chemotherapy, surgery, or exposure to radiation. All of these procedures are extremely dangerous. They destroy the body’s immune system, and many patients do not die because of the cancer, they die because their body cannot survive an infection, which they would not have if their immune system was close to being healthy. My family member survived and is still alive and healthy, but still lives in fear of cancer.
Right after my family member’s surgery and before her release from the hospital, I found myself in a serious discussion with a doctor who told me about a German Biochemist, named Dr. Otto Warburg. He discovered the “cause of cancer back in 1923”. The doctor wrote a book titled, “The Metabolism of Tumors”, and in the book he demonstrated the primary cause of cancer as the replacement of oxygen in the respiratory chemistry of normal cells by the fermentation of sugar. The doctor’s finding was that the fermentation process can only be initiated in the relative absence of oxygen. Today there is no recognition of Dr. Warburg’s work by western medicine. But in alternative medicine there is a growing movement pushing such things as keeping the body in an alkaline state, rather than in an acidic state.
Quercetin is a major breakthrough. Research has demonstrated that it has a large number of qualities that protect a person from cancer, and at the same time will act to help cure a cancer patient. These qualities are becoming even more evident as researchers combine quercetin with other natural compounds to
Quercetin has demonstrated a number of qualities that have caused researchers to not to question its ability to prevent cancer. Quercetin has the ability to stifle cell proliferation, and improve programmed cell death; minimizing DNA damage. These qualities have created an interest as a cancer-preventive nutrient. There is also evidence from epidemiologic studies that strongly recommend quercetin and resveratrol correlate a reduced risk of certain cancers. Research studies have shown quercetin’s ability to prevent or slow tumor development including cancers of the brain, liver, colon, and other tissues.
Research and Clinical evidence of quercetin’s effective usefulness in preventing cancer as well as use in therapy is quickly building up. There was an early Phase I clinical trial of quercetin in patients with a variety of cancer types. Nine patients out of the total eleven patients in the study experienced a decrease in enzymes activity needed for tumor growth. There were also two patients suffering from advanced cancer that had not responded to chemotherapy. Both of the patients responded to the quercetin with important drops in chemical tumor markers during the period of the study.
The Cleveland Clinic oncologists recently examined the use of quercetin in patients with familial adenomatous polyposis (an inherited condition that produces hundreds of colonic polyps which become cancerous). Quercetin was combined with curcumin, curcumin is also known as anti-inflammatory and tumor blocking nutrient. They treated five patients with this combination and followed them for six months. At the end of six months all five patients had a reduction in both tumor size (60%) and the number of polyps (51%). There were minimal adverse effects and no evidence of laboratory abnormalities. Because the study results were so successful the researchers are trying to develop a larger controlled trial to explore the use of the supplements potential cancer prevention and fighting abilities.
I hope this information will give the reader reason to ask their doctor direct questions if they are facing a problem involving cancer. Today we know the drug companies do not have any drugs that prevent or cure cancer. We know that today there are natural compounds that will give effective help in preventing and caring for cancer. At the top of my list are quercetin, resveratrol, curcumin, and vitamin D3.
Wednesday, April 15, 2009
Quercetin - Improves Heart Health
Heart disease is a major killer in America. Research has found that quercetin and resveratrol can have a direct link to the solving of this horrible problem. Researchers have found that if an individual increases the dietary intake of quercetin-rich foods he should experience a reduction in the risk of heart disease being the cause of death. Spanish researchers found in 2000, red wine carrying quercetin and related antioxidants, restricted activity of inflammation-promoting NF-kappa in human volunteers, furnishing a large part of the explanation of how red wine lowers heart disease mortality.
British researchers demonstrated in 2004, that when human’s ingested quercetin supplements there was substantial lessening of platelet aggregation, indicating another of quercetin’s cardiovascular health benefits is related to lowering the risk of clotting. Later, this same group of researchers demonstrated that dietary intake of quercetin from onion soup also helped stop platelet aggregation. In another study of 30 men with heart disease, Greek cardiologists demonstrated that a red grape polyphenol extract rich in quercetin produced an increasing flow-mediated dilation of the major arteries, this was a potent indicator of improved endothelial health.
What happens if a person uses quercetin supplements alone and how would they affect their blood pressure? The University of Utah created a study in 2007 to answer this question. Nineteen students in the study had pre-hypertension and then there were twenty two more students with stage 1 hypertension. Each student was supplemented with either a placebo or 730 mg quercetin per day for a total of 28 days. Pre-hypertensive patients were not affected by the supplements. However, the hypertensive group experienced a reduction in both systolic and diastolic blood pressure; averaging 7mmHg and 5mmHg reductions, these changes were meaningful changes that lowered the vascular disease risk.
A second study, in 2008, a randomized, placebo-controlled cross over trial in 12 healthy men showed biochemical evidence of improved endothelial function with as little as 200 mg/day quercetin.
When you put these studies together, the study results point to how quercetin can carry out an important role in protecting cardiovascular health.
I just found another point I would like to make you aware of. I found this information when I checked with Vitamin Research Products and found this information prepared by their Staff.
In short they have found research that shows quercetin is involved in regulating a gene that protects against LDL cholesterol oxidation. Paraoxonase 1 (PON1) protects low – density lipoprotein (LD) cholesterol from the oxidation process. PON 1 is a major anti-atherosclerotic protein component of the “good” cholesterol, high density lipoprotein (HDL) cholesterol.
In one study the researchers investigated the role quercetin played in regulating PON1 expression in rats. In short, the researchers found that quercetin increased the rats receiving quercetin had an increased expression of PON1 by 35%, and serum PON1 increase of 29 percent.
The study authors concluded, “Our data suggest that quercetin has antiatherogenic effect by up regulating PON1 gene expression and its protective capacity against LDL oxidation”
Let me add one other thought. Quercetin is an anti-inflammatory supplement. Inflammation has a direct affect on the total coronary and will kill you if it is not controlled. But the inflammation does not limit it self to just the coronary system. If you have sore joints it is because of inflammation. So quercetin has a very broad impact on the body.
Yes this is another reason why I am using quercetin. I have a sore back and really bad knee. So I had a lot of inflammation and the quercetin has really helped cut the pain.
Tuesday, April 14, 2009
Quercetin : Anti-Infection & Anti-Obesity
Garlic has almost 200 compounds. Garlic has been used for centuries to treat and prevent infectious diseases and viral complication. Quercetin is one of the 200 compounds in garlic. Modern science has verified quercetin benefits in preventing viral diseases. Laboratory research on quercetin has acted to reduce reproduction and infection of many viruses, including respiratory syncytial virus (a common causative agent of children’s upper respiratory infection).
Last year Italian researchers discovered that an extract rich in quercetin has an ability to protect cells infected with herpes viruses. Then an animal study conducted last year showed that when the test animals were supplemented with quercetin, it aided the mice so they were not infected with the influenza after exercise-induced stress. This finding will be used to support future research. Already there are studies using combinations of quercetin and curcumin; another is, of course, quercetin & resveratrol.
Obesity is rapidly becoming one of Earth’s major global health problems. Quercetin has captured the interest of obesity research as they are exploring quercetin’s potential as a method to control fat accumulation. In the past fat was considered inert. Now, it is known and accepted that fat is a beehive of endocrine and metabolic activity producing hormones, inflammatory cytokines and other molecules which influence health both good and bad.
Exciting research shows that this flavonoid can by itself or in combination with resveratrol and genistein have the ability to exert multiple effects directly on fat tissue. Fat accumulation in aging human fat cells is restricted in culture; this will stop the aging of new fat cells and simultaneously begins apoptosis (the programmed destruction of existing fat cells). Quercetin acts to block the intake of glucose from the blood, this prevents fat cells from getting fresh raw materials required to produce and collect fat molecules. A University of Georgia research group published an important report in 2008, in which they reported they could stop fat cell production and increase fat cell death by using either resveratrol or quercetin. When they combined quercetin and resveratrol the lipid accumulation was sharply reduced in cultured fat cells by nearly 70%, and increased fat cell apoptosis by an amazing 310%.
Animal studies have produced evidence to support the potential anti-obesity qualities of quercetin. It is no surprise that quercetin alone or in combination with nutraceuticals is gaining so much attention from researchers hunting for an effective technology to block obesity and its many harmful effects on human health and vigor.
I will be using quercetin and possible combinations of quercetin and other nutraceuticals, as information is published on what is being developed. What excites me is that both quercetin and resveratrol have so much to offer in improving human health, and at the same time they have no dangerous side effects to be afraid of. Oh yes, there is another very important advantage to using these supplements, they are very affordable. I will keep my progress updated in the blog.
Sunday, April 12, 2009
QUERCETIN - AMAZING COMPOUND
I am sure almost everyone has heard how the French people are able to eat such rich food and enjoy the benefits of red wine. Scientific revelations have shown red wine has a number of valuable polyphenols, such as resveratrol and quercetin.
Quercetin has long been known for its anti-inflammatory and anti-allergic qualities, and both of these qualities have been supported recently by scientific breakthroughs. These breakthroughs have also brought attention to quercetin’s ability to promote life extension by imitating caloric restriction. It demonstrates the many-sided protective benefits against cardiovascular disease, metabolic syndrome and even cancer. Quercetin can be found in red wine and other dietary sources, such as apples, onions, grapefruit, tea, green vegetables and beans. A highly-purified supplement makes it possible to get strictly-controlled biological doses showing promise to prevent disease.
The heart of Quercetin’s amazing properties is its abilities to modulate the inflammation. It is understood inflammation is involved in all of the chronic human diseases and most of the acute infections. In 2007 Korean researchers demonstrated how quercetin restricted the production of inflammatory cytokines and blocked effects of a cellular mediator NF-kappa B, which has been long associated with cancer and chronic inflammatory conditions. Pharmaceutical agents will act to block COX enzymes used to manage painful conditions like arthritis, and LOX enzymes are used to manage asthma.
Research has successfully built a solid foundation for the importance of quercetin in treating human medical disorders. New research will use this foundation to further develop a better understanding of what quercetin can do for mankind. I am sure this will bring a brighter and healthier future for the world.
Sunday, March 15, 2009
Prevent the Ravages caused by Type-1 & Type-2 Diabetes
In today’s mail I received my latest copy of Dr. Robert Jay Rowen’s newsletter, SECOND OPINION. I have a lot of respect for Dr. Rowen’s approach to today’s form of medicine, because I have found he is trying to open our minds to allow all of us to see the many different views of how we can deal with our health and not be regimented by the controlling medical power structure.
Diabetes is one of the monster chronic diseases that have become an industry worth billions of dollars and Dr. Rowen has touched on a way to block some of the ravages caused by Type 1 & Type 2 Diabetes. At first I was not interested in reading his article, as I do not have diabetes, but a voice told me to read it anyway. He made his point in the first sentence, “….. You have a very high risk of getting severe vascular disease. In particular, high blood sugar leads to more Age Related Glycation (AGE) productions. …suffer a loss of an important vascular protecting enzyme called prostacyclin - - - up to 70%.” This is bad, but it does not end there. Because you can also suffer tissue damage caused by an increase in monocyte hexosamine-modified proteins. Yes this is scary, but there is an effective method for overcoming these dangers.
Dr. Rowen quickly touched on two studies that have just been reported, one study on rodents and the other on humans. The studies showed that two key nutrients can reverse all of the above damage.
Alpha lipoic acid and benfotiamine are the key nutrients that can reverse the tissue damage. Benfotiamine is a superior sulfur-bearing and lipid –soluble form of Vitamin B1. The rodent study found both nutrients improved the chemical injury markers. Yet, the human study produced the most impressive results.
The human study showed that alpha lipoic acid and benfotiamine completely normalized the increase AGE. There were also reductions in monocyte hexosamine-modified proteins by 40% and normalized the 70% decrease in prostacyclin production.
Dr. Rowen said he has used both of the supplements for years in type-2 diabetes. He recommends the following, “no matter what form of diabetes you have, -- consider 100 mg daily of benfotiamine and 300mg daily of alpha lipoic acid. You should be able to find both of these supplements online or in health food stores.
Ref: Du, X., M. Brownlee, et al. “Benfotiamine plus alpha-lipoic acid normalizes complication-causing pathways in type-1diabetes,” Diabetolgia, 2008 July 29; [Epub ahead of print]].
RESVERATROL - ABSOLUTELY AMAZING
A new Harvard Medical School study says that it might be possible to eat the wrong foods and still have more energy, a healthy heart, liver and arteries; using resveratrol would give you more stamina, and greater mental clarity.
This new study may have found a way to overcome the negative effects of a high-calorie diet loaded with trans-fats. They used resveratrol to accomplish these successes. I am sure you know that resveratrol is bioflavonoid found in red grape skins. Earlier research has shown that resveratrol supports your heart, healthy blood flow. Now, scientist think resveratrol can act to keep you healthy even if you eat all the wrong foods.
The Harvard researchers wanted to know if resveratrol could help us live longer, healthier lives. To get the answer, they set up a research project using a group of middle aged mice, divided into two groups. One group of mice was fed a really bad junk food diet; 60% of the calories came from fat, including Trans fats. Yes Sir, this group of mice got very fat and developed a long list of health problems, i.e. bloated livers, insulin resistance, and strained cardiovascular systems. They died prematurely.
Amazing, the second group of mice, eating the same exact diet at the same time did not have any health problems. The big difference is that this group of mice was given resveratrol.
What were the results? Yes, the mice did become overweight, but they looked healthy and their organs functioned in a healthy manner as thin mice would function. The big surprise is that the resveratrol mice lived 15% longer.
The researchers did not stop there. It was decided to put the overweight mice through endurance tests against normal, thin mice. The fat mice had twice the stamina and agility as the thin mice; that was considered incredible. It was concluded that these overweight mice performed in such an exceptional manner because resveratrol increased blood flow and charged their muscles with energy.
A similar study was carried out by the Institute of Genetics and Molecular and Cellular Biology. In this study they put mice on treadmills and measured how far they’d run before collapsing. The average mouse was able to run 1 kilometer. Mice fed resveratrol were able to run 2 kilometers.
Based on the results of these two studies, it has been concluded that resveratrol helps to give a person a longer life and it also give you more energy to enjoy life.
What Makes this Happen?
Every cell has a small furnace inside the nucleus, it is called mitochondria. The mitochondria burn nutrients and fats into energy. The faster the metabolism, the more energy the body has. The faster your metabolism, the quicker you burn unnecessary fats so they do not get stored as fat in the body causing health problems.
As we age, our mitochondria start to degenerate and so our metabolism slows down. Good news, resveratrol increases mitochondria production by activating a protein call SIRT-1; and this creates mitochondria. Thus we get an increase in energy, helps maintain healthy blood pressure, healthy blood sugar and protects your liver.
Sunday, March 8, 2009
TIME FOR THE TRUTH
Ok, your doctor gives you bad news after he finishes his exam. You are sick and need to take the drugs he is prescribing. Does he tell you what side effects are produced by the prescribed drugs? No Does he explain how dangerous some of these side effects may be? NO. He does not have time and goes on to the next patient. You, of course, think the medicine is going to make you feel healthy and fit, so you pay your bill and leave the doctor’s office. You have no idea what is in the drug, how was it approved or how it was tested before it was approved. In fact, I doubt if you even have any kind of idea how to investigate a drug. The only important thing that concerns you is the cost of the drug and how you can be sure your insurance pays for the drug.
Ok, some time has passed and you have diligently taken your medicine as prescribed. But, you are not getting well. In fact you are feeling lousy. So back to the doctor and he gives you another prescription to deal with the side effects of the first drug. Now do you get well and feel great? NO! Nothing seems to improve.
Enough of this fiction. The average person that goes to a doctor takes no responsibility for their health. They are not motivated to find out what is happening in this MODERN FORM OF MEDICINE WE WORSHIP SO STRONGLY. There are so many options and ways to treat even the worst diseases. Instead we accept the advertising paid for by the drug companies without question, even when there are cases published in the media pinpointing fraud and lethal activities of drugs being prescribed by our doctors. Here are two recent examples of the fraud and illegal activities being carried out by the drug companies with the co-operation of the FDA.
First, let’s talk about (elithromycin) known as Ketek. Ketek was approved by the FDA to treat mild-to-moderate pneumonia. But Ketek can cause sudden and serious liver damage. There have been cases of complete liver failure requiring a liver transplant. Still there were patients that could not get the transplant in time and died. The FDA knew about the liver failure, and other side effects, before the FDA approved Ketek. To convince an outside scientific advisory committee to recommend approval of Ketek the FDA knowingly allowed a fraudulent safety study to be presented to the advisory committee. The Senate Investigative committee uncovered the following:
1. FDA accepted a resubmission of a new drug application that included fraudulent safety data.
2. FDA employees knowingly presented the fraudulent study data to the advisory committee responsible for recommending Ketek’s approval or disapproval.
3. FDA approved a pediatric clinical trial of Ketek; it involved infants as young as six months old … There was no concern given to the known toxicities affecting the heart, eyes, liver, and vascular system.
4. FDA instructed its personnel preparing to appear before the advisory committee to present the fraudulent safety data.
5. FDA approved a pediatric clinical trial of Ketek; it involved infants as young as six months old... There was no concern given to known toxicities affecting the heart, eyes, liver, and vascular system.
6. FDA continued to willfully release safety data on Ketek.
While the Senate investigation was being conducted there was also a criminal investigation being conducted. They found that the clinic where the study was supposedly conducted was closed during the time the study was to have been carried out. A number of other inconsistencies were also found. Right after the advisory meeting where the fraudulent data was presented to the committee, the FDA employee who conducted the study was criminally indicted and pled guilty. He received a five year sentence in jail. The FDA is still citing the fraudulent data on Ketek. It would appear, in my opinion, that the FDA has continued to function in this criminal enterprise.
Drug-Induced Suicides. The Senate committee that investigated Ketek discovered another study with fraudulent data. This fraudulent data was used to uphold the approval of a popular antidepressant drug being used by large numbers of people in the US.
A Harvard doctor wrote a report that when Paxil application was presented to the FDA advisory committee in 1991, the “Drug Company improperly put people who had previously attempted suicide into the placebo group.” This made it appear that the Paxil group would have the same or lower rate of suicide as the placebo group. The drug company did this to make it appear as if there was no greater suicidal behavior risk for the placebo or Paxil.
In 2006 the manufacturer of Paxil sent a letter to doctors admitting that the risk of suicidal behavior was 6.7 times higher in study subjects taking Paxil when compared to the placebo group.
Suicide is rated as the 11th leading cause of death in the United States. In 2004 Suicide killed over 32,000 people. “The number of suicides attributed to drugs like Paxil (selective serotonin-reuptake inhibitors) could be in the hundreds of thousands during the 13 years it was fraudulently marketed.”
Wednesday, February 11, 2009
Vitamin D3 Can Save Lives
Vitamin D3 is an absolutely fascinating supplement that I have ignored for a long time. Last month, Life Extension Magazine, January, 2009 issue had a startling article written by the magazine’s editor, William Faloon. MILLIONS OF NEEDLESS DEATHS tells how this vitamin can save lives by preventing heart attack, cancer and stroke. Mr. Faloon has been on a crusade to get our federal government to recognize the benefits of vitamin D3. After almost two years of trying to gain co-operation from the government nothing had happened. But in his 16 months of effort new studies have appeared to show optimizing vitamin D intake will save even more lives than what had been expected.
A study published in June, 2008 showed men with low vitamin D levels suffered 2.42 times more heart attacks. This caused me to look back on an article I read by Chris D. Meletis, ND. It has become clear that this nutrient acts to widen the role of vitamin D3 in an individual’s total health. This has only made it clear that a large percentage of the population at large is deficient in this important nutrient. Faloon made this deficiency even more apparent when he placed the number of Americans dieing each year from coronary artery disease-related heart attacks at 157,000. He went on to say that based on a recent study, if Americans were optimizing their vitamin D status, the number dieing would have been reduced to 92,500, 55% would have been saved.
He put the number of lives into context by pointing out that millions of dollars are being spent to promote Lipitor as reducing heart attacks by 37%. Yes, this is an impressive number; but not when compared to the number of lives that would be saved by vitamin D. He makes the point the latest study, men with higher levels of vitamin D levels had a 142% reduction in heart attacks. This does not mean that you should stop taking your prescribed medications, but it does mean you do not want become vitamin D deficient.
All forms of heart disease kill over 869,700 Americans per year. The lethal forms of heart disease include all of the following: cardiomyopathy, valvular insufficiency, congestive heart failure, arrhythmia, coronary thrombosis (blood clot in coronary artery), and coronary atherosclerosis. It is believed that vitamin D would help to give protection against many of the forms of cardiac-induced death.
Today we are surrounded by an economy that seems to be on the verge of disaster. President Obama is trying to find a solution to our many financial problems. The politicians talk about how health care has to be made more effective and affordable for the average American citizen. Consider these facts; there are 920, 000 heart attacks per year, according to the American Heart Association. Annual cost for health care services, medications, and lost productivity caused by these heart attacks is over $156 billion.
Now compare the annual retail cost of all 300 million Americans supplementing with 1,000 IU of vitamin D is $6.6 billion. This would give us a savings of $149.40 billion. Ok, if vitamin D’s only benefit is to reduce heart attacks by 142%, the net savings (after deducting the cost of vitamin D) would be around$84 billion each year. Do you not agree that would put a huge dent in our national health care cost?
References
1. Available at: http://en.wikipedia.org/wiki/Abiogenesis. Accessed September 4, 2008.
2. Faloon W. Should the president declare a national emergency? Life Extension. 2007 Oct;13(10):7-17.
3. Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and risk of myocardial infarction in men:
a prospective study. Arch Intern Med. 2008 Jun 9;168(11):1174-80.
4. Available at: www.americanheart.org/downloadable/heart/1200082005246HS_Stats%202008.final.pdf. Accessed October 29, 2008.
5. Dobnig H, Pilz S, Scharnagl H, et al. Independent association of low serum 25-hydroxyvitamin d and 1,25-
dihydroxyvitamin d levels with all-cause and cardiovascular mortality. Arch Intern Med. 2008 Jun 23;168(12):1340-9.
Refrences: Chris D. Meletis, ND
4. Hathcock JN, Shao A, Vieth R, Heaney R. Risk assessment for Vitamin D. Am J Clin Nutr. 2007 Jan;85(1):6-18.
5. Vieth R. Critique of the considerations for establishing the tolerable upper intake level for Vitamin D: critical need for revision upwards. J Nutr. 2006 Apr;136(4):1117-22.
6. Wilkins CH, Sheline YI, Roe CM, Birge SJ, Morris JC. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry. 2006 Dec;14(12):1032-40.
7. Lotfi A, Abdel-Nasser AM, Hamdy A, Omran AA, El-Rehany MA. HypoVitaminosis D in female patients with chronic low back pain. Clin Rheumatol. 2007 Mar 22; [Epub ahead of print].
Sunday, January 4, 2009
Introduction to Health Debate
Hi, my name is Dick Miller, and I am just a normal guy that is over 70 years old. I work a full time job and of course I am very concerned about my health. Yes, there are a number of things that frustrate me a great deal about standard, conventional medicine. In many ways it is very corrupt. Yet there are real doctors and others that are trying to clean up the mess and create systems that are so much more successful. In my opinion we have a number of problems that everyone seems to be afraid of. Ignorance on the part of the public at large is one of the major problems and there are those that take advantage of this ignorance to make very large amounts of money by herding the ignorant into health care programs that increase the sales of the drug companies, and treatment methodologies that are very expensive, do not cure the medical problems or they just kill the patients. If we could freely use all of the technologies out there, the average person would be amazed at how they could live a more robust life with out expensive drugs. Heart Disease, Cancer, and Diabetes are serious and very dangerous medical problems. Today these medical problems are multibillion dollar industries that have no intent to find a cure. But fantastic advances have been developed in the field of Alternative Medicine and they are not allowed to make the public aware of these advances.
Today, when I see people sitting in a doctor’s waiting room I get very up set. I doubt if any of those individuals have any real understanding of why they are sick. The majority just accept what ever the doctor tells them to do; buy a prescription, accept the prescribed surgery or what ever medical methodology that is prescribed. Most doctors will not take any time to explain in detail what the problem is, or what the causative factors are. Very few will explain how to control the causative factors; assuming that all that is solved when the prescription is followed.
I went through this type of routine when I had my heart attack. I lay in that parking lot for 2 hours before I had regained the strength to crawl over to my car. I pulled myself into the driver’s seat, by this time I was soaking wet from sweating and hurt like hell. I had to gasp to breath. I drove to a medical center down the street and went into the Emergency room and asked for help. A nurse checked me over and told me there was nothing wrong. I went out to my car and sat there until the pain in my chest and my back stopped and I could breathe without effort. Several months later my regular doctor ordered an electrocardiogram for me. She told me I had a heart attack and I told her what happened. She called a Cardiologist and made an appointment for me. In short, I went through a series of very dangerous and painful tests, which resulted in my diagnosis. The Cardiologist gave me a fist full of prescriptions and restrictions on my life style. He would not answer any of my questions. I went back to my regular doctor and explained what had happen. My doctor got very angry and called the Cardiologist’s office. From that point on my education started on heart disease. She put me on a number of supplements and herbs. I did not understand how the supplements like Coenzyme Q10, L-Carnitine, D-Ribose, or Magnesium did anything to help my heart, but I faithfully did as the doctor directed, and guess what, my pain disappeared, I did not get dizzy, I had more stamina and strength. I was not totally healed, but I was a hell of a lot better. I knew I had to know to know what exactly was wrong with my heart and why I had the problem. So I had a lot of questions. My doctor was a practitioner of Alternative medicine. She answered most of my questions and agreed that I needed to learn more. I asked a lot of questions and I will admit it was not easy. But I was fortunate and started getting more and more answers. One day I called a company that had a top quality D-Ribose supplement and I was asking a lot of pointed questions, because I was not a believer in what this supplement was supposed to do. Finally, the lady I was talking to told me about a book written by Stephen T. Sinatra, a practicing cardiologist in
I would recommend that you check out two magazines. Life Extension magazine, at www.lifeextension.com; they will send you a copy of the magazine for free. It is a terrific publication. I subscribe to the magazine and I am also a member of the Life Extension Foundation. There are a lot of benefits that they have to offer.
Total Health Magazine is another terrific publication. Go to www.totalhealthmagazine.com
I would also like to recommend a book written by Suzanne Somers, BREAKTHROUGH, EIGHT STEPS TO WELLNESS.
I started reading this book in August. It completely stopped me. I had never given Suzanne Somers any real attention. Man was I wrong. She is an accomplished author and really knows the problems of medicine. In the book she interviews some very accomplished doctors and does not hide the shocking details she learns from the doctors. The first doctor she interviewed was one of my heroes, Dr. Jonathan Wright. This is a book that every one has to read before they can really put their health plans together.
I hope you found some of my thoughts valuable and useful. This is a new adventure for me and I am very excited about how I may be able to help people.
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- A STRONG HEART BECAUSE OF QUERCETIN
- CANCER SURVIVAL WITH QUERCETIN & RESVERATROL
- QUERCETIN MAKES MY HEART HEALTHY
- CANCER TRIALS AND FAILURE
- QUERCETIN & RESVERATROL BEAT OBESITY
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