The articles I have already posted have been a challenge, because they open the door to such amazing possibilities for improving our health. But it is obvious to me that we are only looking at what I believe will become real in the future. So I have been taking a look at what is being done in research and I have found two research projects that I believe are important and a good way to close this exploration of quercetin.
A green tea component, epicatechin, has been combined with quercetin flavonoids to improve endothelial function; this is an important marker of cardiovascular health, in a new human trial.
The cells lining blood vessels are called endothelial. Normally endothelial cells lose their flexibility as we age. It was the object of one research study to learn if green tea component could improve the endothelial function in 12 healthy men. Each member of this group was given 200 mg quercetin, epicatechin, epigallocatechin gallate or a placebo. Nitric oxide was used to determine if the flavonoids were having a beneficial effect on the blood vessel endothelial cells. Nitric oxide was used because it causes the cells to become more flexible and will only work if the rigidity of the cells has been reduced, giving them the ability to expand. Without getting into the technical details of the study, the conclusion was that quercetin and epicatechin, can boost nitric oxide status and reduce endothelin-1 concentrations, improving endothelial function.
Quercetin and Curcumin Found Important for Colon Health
Research is indicating that when quercetin and curcumin, a turmeric-derived component, could possibly reduce precancerous polyps in people who have an inherited tendency to develop colon cancer.
The current study worked to evaluate the effect of the combination of curcumin and quercetin to retard adenomas in patients with FAP. The study had five FAP patients with prior colectomy; each received 480 mg of curcumin and 20 mg of quercetin. The study found the number of polyps were reduced from the start of the project by a mean of 60.4 percent and the size of the polyps were reduced by 50.9 percent. There were minimal negative side effects and no laboratory abnormalities were noted.
In conclusion, it was found that curcumin and quercetin acted to reduce the number and size of ileal and rectal adenomas in patients with FAP without any appreciable toxicity. The researchers are trying to develop and operate randomized controlled trials to validate their findings.
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