Monday, June 22, 2009

QUERCETIN & RESVERATROL BEAT OBESITY

I have had a number of health problems in 72 years and one of the toughest for me has been to keep my weight down. When I discovered quercetin, I was surprised and really question the information I was reading about the research on quercetin and obesity. But, I have to admit, it is really hard to ignore the facts as presented by the research findings.


Obesity is rapidly becoming one of Earth’s major global health problems. Quercetin has captured the attention of scientists and they are eagerly exploring quercetin’s potential as a technology to control fat accumulation. Fat has long been considered inert; a biologically uninteresting tissue. Now science knows the old idea that fat is inert is totally wrong. Today, fat is considered, by many in science, to be a beehive of endocrine activity and metabolic activity producing a large number of hormones, inflammatory cytokines and other molecules which influence health, both good and bad.

Recent research is very exciting; it shows that this flavonoid can by itself or in combination with resveratrol and genistein, have the ability to exert multiple effects directly on fat tissue.

Fat accumulation in aging human fat cells is restricted in culture. This also stops the aging of new fat cells and simultaneously starts apoptosis (the programmed destruction of existing fat cells). Quercetin works to block the intake of glucose from the blood. This deprives fat cells from receiving the raw material needed to produce and gather fat molecules. A University of Georgia research group published a striking report in 2008 in which they reported they could stop fat cell production and increase fat cell death by using either resveratrol or quercetin. When they combined resveratrol and quercetin, lipid accumulation was sharply reduced in cultured fat cells by nearly 70%, and increased fat cell apoptosis by an amazing 310%.

Animal studies have shown support to the potential anti-obesity qualities of quercetin. It is no surprise that quercetin alone or in combination with other nutraceuticals is receiving so much attention from researchers trying to find an effective methodology to block obesity and its many harmful effects on human health and vigor.

Quercetin is a wide spread polyphenol found in apples, onions, and red grapes and has been ignored for years, so others in its class have received all of the attention... In the last two years there has been a tremendous increase in information emerging about the versatile molecule. It is now understood that quercetin fundamentally affects disease processes as different as cancer, obesity, heart disease and asthma. The effects of its powerful antioxidant will reduce inflammation throughout the body. The most astonishing effect is that quercetin may have a direct and independent influence in prolonging life itself, the mechanisms of which are becoming less mysterious to science as they are attracted to the deep inside cellular processes.

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