Thursday, April 16, 2009

QUERCETIN & CANCER SURVIVAL

QUERCETIN & CANCER SURVIVAL

No, I have never had cancer, but members of my family have gone through the hell of cancer. I saw nothing to impress me in the way western medicine cared for the family member. I did not see any thought of innovative care or interest in finding a way to fight the cancer. What I saw was a group of robots that treated every cancer patient the same way; patients and their families were no different. There was absolute acceptance of their doom. The fatalistic depression gave these so-called doctors total freedom to do anything they chose to do. All of their brilliant treatments centered on the same series of treatment; chemotherapy, surgery, or exposure to radiation. All of these procedures are extremely dangerous. They destroy the body’s immune system, and many patients do not die because of the cancer, they die because their body cannot survive an infection, which they would not have if their immune system was close to being healthy. My family member survived and is still alive and healthy, but still lives in fear of cancer.

Right after my family member’s surgery and before her release from the hospital, I found myself in a serious discussion with a doctor who told me about a German Biochemist, named Dr. Otto Warburg. He discovered the “cause of cancer back in 1923”. The doctor wrote a book titled, “The Metabolism of Tumors”, and in the book he demonstrated the primary cause of cancer as the replacement of oxygen in the respiratory chemistry of normal cells by the fermentation of sugar. The doctor’s finding was that the fermentation process can only be initiated in the relative absence of oxygen. Today there is no recognition of Dr. Warburg’s work by western medicine. But in alternative medicine there is a growing movement pushing such things as keeping the body in an alkaline state, rather than in an acidic state.

Quercetin is a major breakthrough. Research has demonstrated that it has a large number of qualities that protect a person from cancer, and at the same time will act to help cure a cancer patient. These qualities are becoming even more evident as researchers combine quercetin with other natural compounds to

Quercetin has demonstrated a number of qualities that have caused researchers to not to question its ability to prevent cancer. Quercetin has the ability to stifle cell proliferation, and improve programmed cell death; minimizing DNA damage. These qualities have created an interest as a cancer-preventive nutrient. There is also evidence from epidemiologic studies that strongly recommend quercetin and resveratrol correlate a reduced risk of certain cancers. Research studies have shown quercetin’s ability to prevent or slow tumor development including cancers of the brain, liver, colon, and other tissues.

Research and Clinical evidence of quercetin’s effective usefulness in preventing cancer as well as use in therapy is quickly building up. There was an early Phase I clinical trial of quercetin in patients with a variety of cancer types. Nine patients out of the total eleven patients in the study experienced a decrease in enzymes activity needed for tumor growth. There were also two patients suffering from advanced cancer that had not responded to chemotherapy. Both of the patients responded to the quercetin with important drops in chemical tumor markers during the period of the study.

The Cleveland Clinic oncologists recently examined the use of quercetin in patients with familial adenomatous polyposis (an inherited condition that produces hundreds of colonic polyps which become cancerous). Quercetin was combined with curcumin, curcumin is also known as anti-inflammatory and tumor blocking nutrient. They treated five patients with this combination and followed them for six months. At the end of six months all five patients had a reduction in both tumor size (60%) and the number of polyps (51%). There were minimal adverse effects and no evidence of laboratory abnormalities. Because the study results were so successful the researchers are trying to develop a larger controlled trial to explore the use of the supplements potential cancer prevention and fighting abilities.

I hope this information will give the reader reason to ask their doctor direct questions if they are facing a problem involving cancer. Today we know the drug companies do not have any drugs that prevent or cure cancer. We know that today there are natural compounds that will give effective help in preventing and caring for cancer. At the top of my list are quercetin, resveratrol, curcumin, and vitamin D3.

Wednesday, April 15, 2009

Quercetin - Improves Heart Health

When I decided to write my blog I had one fundamental reason, and it was a very personally selfish reason. I wanted to learn how to stay healthy. I was really tired of being sick. I have had a heart attack and laid on that blacktop in a parking lot for a very long time before I was able to do anything but cough and force myself to breath. When I finally crawled to my car and pulled myself inside I could not believe how much my back and chest hurt. It felt like I had been shot several times. About five or six weeks later my doctor agreed to see me and told me I had a bad heart. I lost my temper and decided I had to find a way to take care of myself. It has now been several years since the attack, and in my last physical I was told my heart is really strong & healthy. I accomplished this by refusing to take any drugs. It has been a constant search for alternative methods that have given me the good health I have today. I hope you can see why quercetin is so important to me. This is a quick examination of how it helps the heart and eliminates the use of drugs, whose side effects are many times more dangerous than if you take no medication. It is also a lot more affordable.

Heart disease is a major killer in America. Research has found that quercetin and resveratrol can have a direct link to the solving of this horrible problem. Researchers have found that if an individual increases the dietary intake of quercetin-rich foods he should experience a reduction in the risk of heart disease being the cause of death. Spanish researchers found in 2000, red wine carrying quercetin and related antioxidants, restricted activity of inflammation-promoting NF-kappa in human volunteers, furnishing a large part of the explanation of how red wine lowers heart disease mortality.

British researchers demonstrated in 2004, that when human’s ingested quercetin supplements there was substantial lessening of platelet aggregation, indicating another of quercetin’s cardiovascular health benefits is related to lowering the risk of clotting. Later, this same group of researchers demonstrated that dietary intake of quercetin from onion soup also helped stop platelet aggregation. In another study of 30 men with heart disease, Greek cardiologists demonstrated that a red grape polyphenol extract rich in quercetin produced an increasing flow-mediated dilation of the major arteries, this was a potent indicator of improved endothelial health.

What happens if a person uses quercetin supplements alone and how would they affect their blood pressure? The University of Utah created a study in 2007 to answer this question. Nineteen students in the study had pre-hypertension and then there were twenty two more students with stage 1 hypertension. Each student was supplemented with either a placebo or 730 mg quercetin per day for a total of 28 days. Pre-hypertensive patients were not affected by the supplements. However, the hypertensive group experienced a reduction in both systolic and diastolic blood pressure; averaging 7mmHg and 5mmHg reductions, these changes were meaningful changes that lowered the vascular disease risk.

A second study, in 2008, a randomized, placebo-controlled cross over trial in 12 healthy men showed biochemical evidence of improved endothelial function with as little as 200 mg/day quercetin.

When you put these studies together, the study results point to how quercetin can carry out an important role in protecting cardiovascular health.

I just found another point I would like to make you aware of. I found this information when I checked with Vitamin Research Products and found this information prepared by their Staff.

In short they have found research that shows quercetin is involved in regulating a gene that protects against LDL cholesterol oxidation. Paraoxonase 1 (PON1) protects low – density lipoprotein (LD) cholesterol from the oxidation process. PON 1 is a major anti-atherosclerotic protein component of the “good” cholesterol, high density lipoprotein (HDL) cholesterol.

In one study the researchers investigated the role quercetin played in regulating PON1 expression in rats. In short, the researchers found that quercetin increased the rats receiving quercetin had an increased expression of PON1 by 35%, and serum PON1 increase of 29 percent.
The study authors concluded, “Our data suggest that quercetin has antiatherogenic effect by up regulating PON1 gene expression and its protective capacity against LDL oxidation”

Let me add one other thought. Quercetin is an anti-inflammatory supplement. Inflammation has a direct affect on the total coronary and will kill you if it is not controlled. But the inflammation does not limit it self to just the coronary system. If you have sore joints it is because of inflammation. So quercetin has a very broad impact on the body.

Yes this is another reason why I am using quercetin. I have a sore back and really bad knee. So I had a lot of inflammation and the quercetin has really helped cut the pain.

Tuesday, April 14, 2009

Quercetin : Anti-Infection & Anti-Obesity

I found Quercetin to be an amazing compound when I explored its capabilities as an anti-inflammatory and anti-allergic compound. This became very important to me because of its function to control infection and obesity. I am over seventy years old and I have fought the battle trying to get my hormones, especially testosterone, up to a healthy level. I have built up a good quantity of belly fat, and I have tried a lot of products that were supposed to help me lose weight, but the fat accumulated in the stomach area, is really hard to get rid of. I have put together a brand new health program for myself. The program will combine a number of different elements, but basically it will use a body building program with a gym called NIFTY after FIFTY; which I think is a terrific program for seniors. Quercetin will fit into this program because of the many things it does to help the body grow and stay healthy. I think the one element of Quercetin that is important for me is its ability to control infection. Nifty after Fifty is a very clean facility, but there is constant turnover of people as they come and go from their workout sessions. So there is always a chance of being exposed to a viral contaminate that Quercetin will give me protection.

Garlic has almost 200 compounds. Garlic has been used for centuries to treat and prevent infectious diseases and viral complication. Quercetin is one of the 200 compounds in garlic. Modern science has verified quercetin benefits in preventing viral diseases. Laboratory research on quercetin has acted to reduce reproduction and infection of many viruses, including respiratory syncytial virus (a common causative agent of children’s upper respiratory infection).

Last year Italian researchers discovered that an extract rich in quercetin has an ability to protect cells infected with herpes viruses. Then an animal study conducted last year showed that when the test animals were supplemented with quercetin, it aided the mice so they were not infected with the influenza after exercise-induced stress. This finding will be used to support future research. Already there are studies using combinations of quercetin and curcumin; another is, of course, quercetin & resveratrol.

Obesity is rapidly becoming one of Earth’s major global health problems. Quercetin has captured the interest of obesity research as they are exploring quercetin’s potential as a method to control fat accumulation. In the past fat was considered inert. Now, it is known and accepted that fat is a beehive of endocrine and metabolic activity producing hormones, inflammatory cytokines and other molecules which influence health both good and bad.

Exciting research shows that this flavonoid can by itself or in combination with resveratrol and genistein have the ability to exert multiple effects directly on fat tissue. Fat accumulation in aging human fat cells is restricted in culture; this will stop the aging of new fat cells and simultaneously begins apoptosis (the programmed destruction of existing fat cells). Quercetin acts to block the intake of glucose from the blood, this prevents fat cells from getting fresh raw materials required to produce and collect fat molecules. A University of Georgia research group published an important report in 2008, in which they reported they could stop fat cell production and increase fat cell death by using either resveratrol or quercetin. When they combined quercetin and resveratrol the lipid accumulation was sharply reduced in cultured fat cells by nearly 70%, and increased fat cell apoptosis by an amazing 310%.

Animal studies have produced evidence to support the potential anti-obesity qualities of quercetin. It is no surprise that quercetin alone or in combination with nutraceuticals is gaining so much attention from researchers hunting for an effective technology to block obesity and its many harmful effects on human health and vigor.

I will be using quercetin and possible combinations of quercetin and other nutraceuticals, as information is published on what is being developed. What excites me is that both quercetin and resveratrol have so much to offer in improving human health, and at the same time they have no dangerous side effects to be afraid of. Oh yes, there is another very important advantage to using these supplements, they are very affordable. I will keep my progress updated in the blog.

Sunday, April 12, 2009

QUERCETIN - AMAZING COMPOUND

I am a lover of good red wine and in the last week or so I got into one of those deep discussions with my wife and several other people regarding wine and of course, this only led to a number of questions I could not answer. This has motivated me to investigate this amazing Enhanced Antioxidant that protects the heart against heart disease, cancer, allergies, obesity and offers elements to increase our longevity.

I am sure almost everyone has heard how the French people are able to eat such rich food and enjoy the benefits of red wine. Scientific revelations have shown red wine has a number of valuable polyphenols, such as resveratrol and quercetin.

Quercetin has long been known for its anti-inflammatory and anti-allergic qualities, and both of these qualities have been supported recently by scientific breakthroughs. These breakthroughs have also brought attention to quercetin’s ability to promote life extension by imitating caloric restriction. It demonstrates the many-sided protective benefits against cardiovascular disease, metabolic syndrome and even cancer. Quercetin can be found in red wine and other dietary sources, such as apples, onions, grapefruit, tea, green vegetables and beans. A highly-purified supplement makes it possible to get strictly-controlled biological doses showing promise to prevent disease.

The heart of Quercetin’s amazing properties is its abilities to modulate the inflammation. It is understood inflammation is involved in all of the chronic human diseases and most of the acute infections. In 2007 Korean researchers demonstrated how quercetin restricted the production of inflammatory cytokines and blocked effects of a cellular mediator NF-kappa B, which has been long associated with cancer and chronic inflammatory conditions. Pharmaceutical agents will act to block COX enzymes used to manage painful conditions like arthritis, and LOX enzymes are used to manage asthma.

Research has successfully built a solid foundation for the importance of quercetin in treating human medical disorders. New research will use this foundation to further develop a better understanding of what quercetin can do for mankind. I am sure this will bring a brighter and healthier future for the world.

Sunday, March 15, 2009

Prevent the Ravages caused by Type-1 & Type-2 Diabetes

In today’s mail I received my latest copy of Dr. Robert Jay Rowen’s newsletter, SECOND OPINION. I have a lot of respect for Dr. Rowen’s approach to today’s form of medicine, because I have found he is trying to open our minds to allow all of us to see the many different views of how we can deal with our health and not be regimented by the controlling medical power structure.

Diabetes is one of the monster chronic diseases that have become an industry worth billions of dollars and Dr. Rowen has touched on a way to block some of the ravages caused by Type 1 & Type 2 Diabetes. At first I was not interested in reading his article, as I do not have diabetes, but a voice told me to read it anyway. He made his point in the first sentence, “….. You have a very high risk of getting severe vascular disease. In particular, high blood sugar leads to more Age Related Glycation (AGE) productions. …suffer a loss of an important vascular protecting enzyme called prostacyclin - - - up to 70%.” This is bad, but it does not end there. Because you can also suffer tissue damage caused by an increase in monocyte hexosamine-modified proteins. Yes this is scary, but there is an effective method for overcoming these dangers.

Dr. Rowen quickly touched on two studies that have just been reported, one study on rodents and the other on humans. The studies showed that two key nutrients can reverse all of the above damage.

Alpha lipoic acid and benfotiamine are the key nutrients that can reverse the tissue damage. Benfotiamine is a superior sulfur-bearing and lipid –soluble form of Vitamin B1. The rodent study found both nutrients improved the chemical injury markers. Yet, the human study produced the most impressive results.

The human study showed that alpha lipoic acid and benfotiamine completely normalized the increase AGE. There were also reductions in monocyte hexosamine-modified proteins by 40% and normalized the 70% decrease in prostacyclin production.

Dr. Rowen said he has used both of the supplements for years in type-2 diabetes. He recommends the following, “no matter what form of diabetes you have, -- consider 100 mg daily of benfotiamine and 300mg daily of alpha lipoic acid. You should be able to find both of these supplements online or in health food stores.

Ref: Du, X., M. Brownlee, et al. “Benfotiamine plus alpha-lipoic acid normalizes complication-causing pathways in type-1diabetes,” Diabetolgia, 2008 July 29; [Epub ahead of print]].

RESVERATROL - ABSOLUTELY AMAZING

I just read several articles about resveratrol. I was attracted to learning more about resveratrol because some of my friends were giving me a hard time because of my diet. Yes Sir, I am very serious about my health, and taking care of myself. But it seems there are those that do not believe I am personally disciplined to match my image. So I figured I would prove them wrong. Now that the beating is over and I have to admit they are right on some points, I am excited about what I learned about resveratrol.

A new Harvard Medical School study says that it might be possible to eat the wrong foods and still have more energy, a healthy heart, liver and arteries; using resveratrol would give you more stamina, and greater mental clarity.

This new study may have found a way to overcome the negative effects of a high-calorie diet loaded with trans-fats. They used resveratrol to accomplish these successes. I am sure you know that resveratrol is bioflavonoid found in red grape skins. Earlier research has shown that resveratrol supports your heart, healthy blood flow. Now, scientist think resveratrol can act to keep you healthy even if you eat all the wrong foods.

The Harvard researchers wanted to know if resveratrol could help us live longer, healthier lives. To get the answer, they set up a research project using a group of middle aged mice, divided into two groups. One group of mice was fed a really bad junk food diet; 60% of the calories came from fat, including Trans fats. Yes Sir, this group of mice got very fat and developed a long list of health problems, i.e. bloated livers, insulin resistance, and strained cardiovascular systems. They died prematurely.

Amazing, the second group of mice, eating the same exact diet at the same time did not have any health problems. The big difference is that this group of mice was given resveratrol.

What were the results? Yes, the mice did become overweight, but they looked healthy and their organs functioned in a healthy manner as thin mice would function. The big surprise is that the resveratrol mice lived 15% longer.

The researchers did not stop there. It was decided to put the overweight mice through endurance tests against normal, thin mice. The fat mice had twice the stamina and agility as the thin mice; that was considered incredible. It was concluded that these overweight mice performed in such an exceptional manner because resveratrol increased blood flow and charged their muscles with energy.

A similar study was carried out by the Institute of Genetics and Molecular and Cellular Biology. In this study they put mice on treadmills and measured how far they’d run before collapsing. The average mouse was able to run 1 kilometer. Mice fed resveratrol were able to run 2 kilometers.

Based on the results of these two studies, it has been concluded that resveratrol helps to give a person a longer life and it also give you more energy to enjoy life.

What Makes this Happen?

Every cell has a small furnace inside the nucleus, it is called mitochondria. The mitochondria burn nutrients and fats into energy. The faster the metabolism, the more energy the body has. The faster your metabolism, the quicker you burn unnecessary fats so they do not get stored as fat in the body causing health problems.

As we age, our mitochondria start to degenerate and so our metabolism slows down. Good news, resveratrol increases mitochondria production by activating a protein call SIRT-1; and this creates mitochondria. Thus we get an increase in energy, helps maintain healthy blood pressure, healthy blood sugar and protects your liver.

Sunday, March 8, 2009

TIME FOR THE TRUTH

TIME FOR THE TRUTH

Ok, your doctor gives you bad news after he finishes his exam. You are sick and need to take the drugs he is prescribing. Does he tell you what side effects are produced by the prescribed drugs? No Does he explain how dangerous some of these side effects may be? NO. He does not have time and goes on to the next patient. You, of course, think the medicine is going to make you feel healthy and fit, so you pay your bill and leave the doctor’s office. You have no idea what is in the drug, how was it approved or how it was tested before it was approved. In fact, I doubt if you even have any kind of idea how to investigate a drug. The only important thing that concerns you is the cost of the drug and how you can be sure your insurance pays for the drug.

Ok, some time has passed and you have diligently taken your medicine as prescribed. But, you are not getting well. In fact you are feeling lousy. So back to the doctor and he gives you another prescription to deal with the side effects of the first drug. Now do you get well and feel great? NO! Nothing seems to improve.

Enough of this fiction. The average person that goes to a doctor takes no responsibility for their health. They are not motivated to find out what is happening in this MODERN FORM OF MEDICINE WE WORSHIP SO STRONGLY. There are so many options and ways to treat even the worst diseases. Instead we accept the advertising paid for by the drug companies without question, even when there are cases published in the media pinpointing fraud and lethal activities of drugs being prescribed by our doctors. Here are two recent examples of the fraud and illegal activities being carried out by the drug companies with the co-operation of the FDA.

First, let’s talk about (elithromycin) known as Ketek. Ketek was approved by the FDA to treat mild-to-moderate pneumonia. But Ketek can cause sudden and serious liver damage. There have been cases of complete liver failure requiring a liver transplant. Still there were patients that could not get the transplant in time and died. The FDA knew about the liver failure, and other side effects, before the FDA approved Ketek. To convince an outside scientific advisory committee to recommend approval of Ketek the FDA knowingly allowed a fraudulent safety study to be presented to the advisory committee. The Senate Investigative committee uncovered the following:

1. FDA accepted a resubmission of a new drug application that included fraudulent safety data.
2. FDA employees knowingly presented the fraudulent study data to the advisory committee responsible for recommending Ketek’s approval or disapproval.
3. FDA approved a pediatric clinical trial of Ketek; it involved infants as young as six months old … There was no concern given to the known toxicities affecting the heart, eyes, liver, and vascular system.
4. FDA instructed its personnel preparing to appear before the advisory committee to present the fraudulent safety data.
5. FDA approved a pediatric clinical trial of Ketek; it involved infants as young as six months old... There was no concern given to known toxicities affecting the heart, eyes, liver, and vascular system.
6. FDA continued to willfully release safety data on Ketek.
While the Senate investigation was being conducted there was also a criminal investigation being conducted. They found that the clinic where the study was supposedly conducted was closed during the time the study was to have been carried out. A number of other inconsistencies were also found. Right after the advisory meeting where the fraudulent data was presented to the committee, the FDA employee who conducted the study was criminally indicted and pled guilty. He received a five year sentence in jail. The FDA is still citing the fraudulent data on Ketek. It would appear, in my opinion, that the FDA has continued to function in this criminal enterprise.

Drug-Induced Suicides. The Senate committee that investigated Ketek discovered another study with fraudulent data. This fraudulent data was used to uphold the approval of a popular antidepressant drug being used by large numbers of people in the US.

A Harvard doctor wrote a report that when Paxil application was presented to the FDA advisory committee in 1991, the “Drug Company improperly put people who had previously attempted suicide into the placebo group.” This made it appear that the Paxil group would have the same or lower rate of suicide as the placebo group. The drug company did this to make it appear as if there was no greater suicidal behavior risk for the placebo or Paxil.

In 2006 the manufacturer of Paxil sent a letter to doctors admitting that the risk of suicidal behavior was 6.7 times higher in study subjects taking Paxil when compared to the placebo group.

Suicide is rated as the 11th leading cause of death in the United States. In 2004 Suicide killed over 32,000 people. “The number of suicides attributed to drugs like Paxil (selective serotonin-reuptake inhibitors) could be in the hundreds of thousands during the 13 years it was fraudulently marketed.”

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